Review 2006: Artificial bladder transplant success


By Peter Aldhous SEVEN youngsters spared a lifetime of incontinence and kidney infections: that was the heartening outcome that tissue engineer Anthony Atala was able to announce four years after transplanting lab-grown bladders into people born with spina bifida. It is a milestone, to be sure, but one that also shows what a long road lies ahead for tissue engineering. Starting in 2002, Atala and his colleagues at Wake Forest University in Winston-Salem, North Carolina, seeded sacs of collagen with cells from the patients’ own vestigial bladders,
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