The medicine maker: I never thought my work could harm


By Nic Fleming David Nichols describes his shock at discovering his research had been exploited to make “legal highs” – with potentially lethal consequences You work on psychoactive compounds. What are you trying to discover? Initially I was seeking to understand how psychedelic agents like LSD and mescaline interact with the brain. They target a brain receptor that plays a key role in perception and cognition, and we wanted to find the molecular features that give rise to these substances’ effects. My work was at a fundamental level,
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